Ralph Hasenhuettl’s Saints travel to the Tottenham Hotspur Stadium to take on a battered and damaged Spurs side desperate to escape their current rut of poor form.
Tottenham lost on penalties to Colchester United in the League Cup in midweek and have lost ten Premier League games so far in the calendar year of 2019, their most since 2014.
Southampton may have lost the south-coast derby with Bournemouth last Friday, but they are aiming for a third straight away win (available at 7/1).
Saints have scored one goal in all but two of their Premier League fixtures so far. They have also scored in all but one. It is 7/5 for them to score exactly once again.
With forward Moussa Djenepo’s injury worse than expected, will Nathan Redmond, available at 7/2 to net anytime, be able to step-up in the Malian’s absence?
Che Adams, who scored twenty-two goals for Birmingham City in the Championship last season, is yet to bag in his six appearances but he is 3/1 to finally break his top-flight duck anytime.
Spurs last win in all competitions will have been exactly two weeks ago by the time this match comes around. They have played three, losing two and drawing one.
Who better than Harry Kane to rekindle his goal scoring form and save his side from further commiserations? He is 12/5 to score first.
Tottenham’s poor run of form has added more fuel to the fire that is linking manager Mauricio Pochettinho with a move away.
He is currently 3/1 favourite to be the next Manchester United manager and 5/2 to be installed at Real Madrid.
Spurs may be clear 2/5 favourites to win this one, but the ever-patchy and inconsistent Southampton will look to cause even more problems at the new North London ground.
Both teams will surely get on the scoresheet here (3/4).